Bio International Convention 2025: The 9th China (Tianjin) Nucleic Acid Medicine Conference

1. Introduction

In recent years, the field of nucleic acid drugs has made significant progress and has become a hot area with the potential to completely change the way diseases are treated.
Amid this booming trend, Bio International Convention 2025 the 9th China (Tianjin) Nucleic Acid Drug Conference is about to be held.
As an important international platform, the conference will attract experts, researchers, and industry professionals from around the world to gather in Tianjin to discuss, exchange ideas, and explore new frontiers in the field of nucleic acid drugs.

2. Conference Basic Information

2.1 Conference Name:

9th China (Tianjin) Nucleic Acid Drug Conference​

2.2 Date:

September 17–18, 2025

2.3 Location:

Tianjin, China, is a vibrant city renowned for its rich history and rapidly developing biotechnology industry.
Tianjin boasts a convenient transportation network and world-class conference facilities, ensuring a seamless and comfortable experience for all attendees.

3. Professional Conference Framework and Content

3.1 Background and Strategic Significance

Why China? Why Now?

• Global Industry Status:
  • China’s nucleic acid drug industry has become a global core sector with an annual growth rate of over 30%. Of the 24 nucleic acid drugs approved globally, three are from China (such as Ribo Bio’s liver-targeted siRNA drug).
• Policy and Capital Driven:
  • China’s 14th Five-Year Plan for the Bioeconomy specifically supports nucleic acid drugs. In 2024, financing exceeded US$2 billion. Tianjin Economic and Technological Development Zone’s “Ten Policies for the Nucleic Acid Industry” provide R&D subsidies, tax exemptions for equipment, and fast-track approval processes.
• Tianjin’s Hub Value:
  • Leveraging the industrial cluster in the Binhai New Area (such as the 37 member units of the Tianjin Economic and Technological Development Zone Nucleic Acid Industry Alliance) and Free Trade Zone policies, Tianjin has become a strategic hub for international companies entering the Chinese market.

3.2 Core Agenda: Three Technical Breakout Sessions

3.2.1 Breakout Session 1: Innovation and R&D in Small Nucleic Acid Drugs

• AI-Driven Design:
  • Target prediction algorithm optimization (e.g., Sihuo Gene AI platform), novel self-assembling delivery systems (circular aggregation technology breaking through brain targeting bottlenecks).
• Clinical and Regulatory:
  • Former CDE Senior Reviewer Hu Xiaomin interprets differences in regulatory reviews between China, the US, and Europe, and shares case studies on the clinical translation pathways of non-liver-targeted therapies.
• Intellectual Property Protection:
  • Roundtable discussion on patent strategy planning, covering global patent barriers for ASO and siRNA sequence design.

3.2.2 Breakout Session 2: CMC and Industrialization of Small Nucleic Acid Drugs

• Process Pain Point Breakthroughs:
  • Solid-phase synthesis impurity control (Qingke Biotechnology solution), continuous flow production cost reduction path (40% cost compression), GMP multi-standard compliance (FDA/EMA/NMPA).
• Commercialization Logic:
  • Ribo Biotechnology Vice President Tong Cheng analyzes CMC process validation key points, and investment bank analysts discuss orphan drug pricing models.

3.3 Global Trends in Nucleic Acid Drug Development

• Market Outlook:
  • The global market size is projected to reach USD 25 billion by 2025, with China’s share rising to 15% (from 8% in 2023), driven by chronic diseases (such as PCSK9 inhibitors) and tumor vaccines.
• Technological Evolution:
  • Third-generation ASO drugs (enhanced stability) vs. breakthroughs in siRNA extrahepatic delivery (Xingrui Pharma’s non-liver-targeted platform), with China’s Rui Bai Pharma achieving international-standard production capacity through its kilogram-scale GMP production line.

3.4 Comprehensive Analysis of China’s Industry Ecosystem

• Basic Research:
  • The Tianjin International Biomedical Joint Research Institute provides high-throughput screening platforms (serving over 200 projects by 2024).
• Clinical Translation:
  • Youji Pharmaceutical offers one-stop non-clinical evaluation (pharmacodynamics/toxicology/pharmacokinetics) to accelerate IND submissions.
• Commercial Production:
  • CDMO companies like Ruibai Pharmaceutical provide oligonucleotide CRDMO services compliant with FDA/EMA standards.

3.5 Core Value for International Participants

• Regulatory Coordination:
  • NMPA reviewer Hu Xiaomin will provide a dedicated session interpreting differences in submissions between China, the US, and Europe (including clinical endpoint design and CMC data requirements).
• Technical Cooperation:
  • Over 50 company exhibition zones (such as Hanbang Technology’s chromatography purification equipment and General Bio’s FlexFactory production line), with company-specific seminars open for collaboration and networking.
• Investment Opportunities:
  • In Q2 2024, financing in China’s nucleic acid field increased by 40% year-on-year, with early-stage project roadshows (such as AI delivery platforms and circular RNA technology) open to international capital.

3.6 Bio International Convention 2025 Practical Guide for Attendees

3.6.1 Visa and Accommodation:

• The conference organizing committee provides official invitation letters (to assist with business visa applications).
• The designated hotel is the InterContinental Hotel at Jia Bao (600 RMB per night)（Hotel as shown in Figure 1）, with nearby Yado Hotels (380 RMB per night, 700 meters walkable distance). （Hotel as shown in Figure 2）

3.6.2 Transportation Recommendations:

• Beijing Daxing International Airport (PKX) → Tianjin High-Speed Railway (40 minutes, 48 daily departures);
• Tianjin Binhai International Airport (TSN) → 30-minute drive to the venue (shuttle buses arranged by the organizing committee).

3.6.3 Social Networking:

Pre-conference industry discussions on LinkedIn groups, post-conference visits to the Tianjin Biomedical Research Institute Pilot Plant Base (prior reservation required).

3.7 Previous Achievements and Expectations for This Year

• The 8th Conference in 2024 attracted over 800 participants (including 24 international companies) and resulted in 37 cooperation agreements. Technical highlights included:
  • Standardized non-clinical evaluation scheme for small nucleic acids (Youji Pharmaceutical);
  • Key points for oligonucleotide impurity control (RiboO Technology).
• This year’s objectives:
  • Release the “Initiative for the Development of Nucleic Acid Drugs” to promote mutual recognition of international technical standards and cross-border clinical data sharing.

3.8 Organizational Structure and Partners

• Host:
  • China Bio-Pharmaceutical Industry Association (BPIA), China’s only national-level bio-pharmaceutical industry association, with an Expert Committee comprising over 40 academicians.
• Co-organizer:
  • Tianjin International Biomedical Joint Research Institute (national-level incubator), Tianjin Quanhecheng Technology (leading CMC solutions provider).
• Supporters:
  • Agilent (analytical instruments), Hanbang Technology (purification equipment), LGC (reference standards), and other multinational companies.

3.9 Registration Information

• Early Bird Discount (until August 30, 2025):
  • Members: 800 RMB per person; Non-members: 1,200 RMB per person (including conference materials, lunch, and refreshments).
• Payment Methods:
  • Official website supports VISA/PayPal; electronic invoices will be sent to your email.

3.9.1 Other contact information:

• Contact number:
  • 010-67046276
• Business cooperation and booth reservations:
  • Mr. Zhou 17310131518
• Registration confirmation:
  • Mr. Rao 18800170724
• Membership level inquiries:
  • Mr. Cai 18701663551
• Speaker Coordination:
  • Mr. Ma 15565233895
• Registration Fee Invoice Inquiry:
  • Mr. Sun 15313171651
• Paper Submission Email:
  • chinabpiajsb@163.com

4. Other Conference Agenda Highlights: In-Depth Analysis and Interpretation:

4.1 Keynote Speeches:

Renowned experts in the field of nucleic acid drugs from both domestic and international sectors will deliver keynote speeches. They will provide an overview of the global trends in nucleic acid drug development, including the latest advancements in drug design, delivery technologies, and emerging therapeutic applications. For example, some speakers may explore the potential of nucleic acid drugs in treating rare genetic diseases, where traditional therapies have limitations.

4.2 Parallel Sessions:

• Nucleic Acid Drug Design and Synthesis:
  • Sessions under this category will focus on new methods in nucleic acid drug design, such as the development of novel oligonucleotide chemistry and the design of more effective RNA-based drugs. Researchers will share their experiences in optimizing the structure and function of nucleic acid drugs to enhance their efficacy and safety.
• Nucleic Acid Drug Delivery Systems:
  • One of the major challenges in nucleic acid drug development is delivering these drugs to target cells. The parallel session will specifically discuss the latest delivery technologies, including lipid-based nanoparticles, polymer carriers, and viral vectors. Experts will also explore strategies to enhance the targeting and stability of nucleic acid drug delivery systems.
• Clinical Trials and Applications:
  • This section of the agenda will present results from ongoing clinical trials of nucleic acid drugs. Successful application cases in the treatment of cancer, infectious diseases, and neurodegenerative diseases will be discussed. Participants will gain insights into the challenges and opportunities involved in translating nucleic acid drug research from the laboratory to clinical applications.
• Regulatory and Intellectual Property Considerations:
  • Understanding the regulatory environment and protecting intellectual property are critical for the development and commercialization of nucleic acid drugs. The session will cover the latest regulatory requirements across different countries, as well as strategies for protecting intellectual property in this highly competitive field.
• Poster Presentations:
  • A poster presentation session will be held, allowing researchers to showcase their unpublished research findings. This provides a platform for young scientists and researchers to receive feedback from peers and establish connections with potential collaborators. The poster session will cover a wide range of topics related to nucleic acid drugs, from basic research to translational applications.
• Panel Discussions:
  • Industry leaders, regulatory officials, and researchers will participate in panel discussions. These discussions will focus on key issues facing the nucleic acid drug industry, such as future development directions, the impact of emerging technologies, and how to bridge the gap between academia and industry. Open discussions will encourage lively debate and the exchange of different perspectives.

4.3 Attendees:

• Researchers and Scientists:
  • Individuals engaged in nucleic acid drug research, including molecular biologists, biochemists, and pharmaceutical scientists, will find this conference highly valuable. They can learn about the latest research trends, share their work, and explore potential research collaboration opportunities.
• Industry Professionals:
  • Professionals in the pharmaceutical and biotechnology industries, such as drug R&D personnel, R&D managers, and marketing executives, can gain insights into the latest market trends, technological advancements, and regulatory requirements. The conference also offers opportunities to connect with potential partners and suppliers.
• Regulatory Officials and Policy Makers:
  • Staying informed about the latest advancements in nucleic acid drug research is critical for regulatory officials and policymakers. They can use the knowledge gained from the conference to develop more effective regulatory policies and promote the healthy development of the nucleic acid drug industry.
• Investors:
  • In recent years, the nucleic acid drug field has attracted significant investment. Investors can use this conference as a platform to identify promising investment opportunities, meet with innovative companies, and understand the industry’s future growth potential.

5. Bio International Convention 2025 Conclusion:

• The 9th China (Tianjin) Nucleic Acid Drug Conference, scheduled for September 2025, is not merely a gathering but a landmark event in the field of nucleic acid drugs. It offers international participants a unique opportunity for in-depth discussions, learning from top talent in the field, and contributing to the future development of nucleic acid drugs. Whether you are an experienced expert or a newcomer to the field, this conference will undoubtedly provide you with valuable knowledge, connections, and inspiration. Mark your calendars and join us in Tianjin for this grand event!
• This conference serves as a key hub for international participants to decode Chinese policies, connect with technical partners, and strategize for emerging markets. As China’s “Nucleic Acid Drug Valley,” Tianjin invites global innovators to collaborate in building the future of precision medicine through an open ecosystem.
• Nucleic acid drugs are not only a technological revolution but also a cross-border commitment to health—from the laboratory to the bedside, ecological collaboration is the only path forward.

6. Guide to Eating, Drinking, and Entertainment for International Friends Near the Tianjin Nucleic Acid Drug Conference Exhibition Hall

Welcome to Tianjin for the Nucleic Acid Drug Conference!
In your spare time between busy meetings, why not take the opportunity to explore this charming city?
Below is a carefully curated list of popular dining, drinking, and entertainment spots near the exhibition hall and its surroundings, all conveniently located and beloved by international friends.

6.1 Food Recommendations

6.1.1 Old Friends Western Restaurant

• Features:
  • With a bohemian atmosphere, the restaurant offers house-brewed draft beer and a wide selection of imported beers. During the European Cup, many international friends gather here to enjoy drinks, food, and watch the matches.
• Signature Dishes:
  • The pulled pork sandwich is generously portioned, the lasagna features a uniquely flavored sauce, and the filet mignon can be cooked to your preferred doneness, served with crispy fries and a vegetable salad for a nutritious and delicious meal.
• Address:
  • No. 126 Chengdu Road, Heping District, Tianjin City.
• Transportation:
  • Take Metro Line 1 to Yingkou Road Station, then walk approximately 8 minutes to arrive; or take Bus Route 9 or 831 to Yunnan Road Station, then walk 5 minutes to the restaurant. There are bus stops/metro stations near the exhibition hall, and the restaurant is just a few minutes’ walk away.

6.1.2 Ludwig 1308 Beer House

• Features:
  • All beers in the store are homemade. Freshly tapped beer is crisp, with abundant foam, rich flavor, and a smooth texture. Roasted pork knuckle is made from premium pork leg meat, steamed then roasted, with a slightly crispy crust and tender meat, and a subtle smoky flavor upon tasting. German sausages have a chewy skin and tender meat, paired with refreshing sauerkraut, leaving a lasting impression.
• Address:
  • No. 8 Building, Kaixiang Garden, Shuishang Park North Road, Nankai District, Tianjin
• Transportation:
  • From the exhibition hall, take Metro Line 3 to Zhou Enlai and Deng Xiaoping Memorial Hall Station, then walk for about 10 minutes; or take Bus Route 871 or 904 to Shuishang Park North Station, then walk for 3 minutes. The location is convenient, and parking is also readily available in the surrounding area.

6.1.3 Wood Restaurant and Bar

• Features:
  • Outstanding in terms of environment, service, and taste. Each dish is accompanied by an introduction to the origin of its ingredients and the chef’s culinary philosophy. The menu design is warm and thoughtful. The house-made cocktails and non-alcoholic beverages are visually appealing, made with fresh fruits. The Monterey Herb-Smoked Chicken Breast combines Chinese cooking methods with Western spices, and there is a unique pairing of Xinjiang Hami melon with Italian Parma ham.
• Address:
  • 5th Floor, Central Mansion, Hexi District, Tianjin (intersection of Friendship Road and Weidi Road)
• Transportation:
  • Take Metro Line 5 to Southwest Tower Station, then walk approximately 7 minutes to Central Mansion and follow the signs to the restaurant; or take a taxi, which is a short ride from the exhibition hall, costing around 15-20 yuan, a reasonable and convenient option.

6.2 Leisure and Entertainment

6.2.1 Italian Style District

• Features:
  • A national AAAA-level tourist attraction, the former Italian concession covers an area of 0.2845 square kilometers with a total building area of approximately 400,000 square meters. All 137 buildings were designed by Italian architects, including consulates, barracks, schools, and other Western classical structures, making it the only fully preserved Italian-style architectural complex in Asia. The scenic area is adjacent to the Hai River, where visitors can enjoy authentic Italian coffee and pizza while immersing themselves in a rich foreign atmosphere. Street cafes and outdoor seating create the feeling of being on an Italian street corner. An “Italian Culture Festival” is held annually.
• Activities:
  • Stroll and admire Italian-style architecture, visit the former residences of prominent figures such as Liang Qichao’s Drinking Ice Room and Cao Yu’s former residence; enjoy leisurely moments in cafes; savor Italian cuisine; Watch street performances.
• Address:
  • Hebei District, Tianjin, is surrounded by Wujing Road, Boai Road, Shengli Road, and Jiangu Road.
• Transportation:
  • There are buses or subways near the exhibition hall that can take you directly to Tianjin Station. From Tianjin Station, it is only a five-minute walk to the Italian Style District. You can also take subway lines 2, 3, or 9 and get off at Jiangu Road or Tianjin Station subway stations, then walk to the destination.

6.2.2 Wudao Road

• Features:
  • This area features over a hundred uniquely styled Western-style villas, resembling a European town. During the early morning or evening, the soft light makes it ideal for strolling and photography. You can rent a bicycle to leisurely explore the neighborhood and experience the slow-paced lifestyle.​
• Activities:
  • Visit the various Western-style buildings to learn about history and culture; relax at a street-side café; enjoy street performances.
• Address:
  • Located in the southern part of Tianjin’s central urban area (at the junction of Heping District and Hexi District, primarily along the five roads of Machang Road, Munan Road, Dali Road, Changde Road, and Chongqing Road).
• Transportation:
  • Take the Metro Line 1 from the exhibition hall and get off at Xiaobailou Station. It is approximately a 10-minute walk to the Wudao area. Alternatively, take Bus Route 9 or 831 and get off at Machang Road Station, then walk to the scenic area. If you choose to take a taxi, the journey is also quite convenient.

6.2.3 Tianjin Eye Ferris Wheel

• Features:
  • From the Ferris wheel, you can overlook the European-style buildings along both sides of the Hai River. At dusk, as the sky grows dark and the lights come on, the scenery is breathtaking.
• Activities:
  • Ride the Ferris wheel to enjoy the beautiful views of Tianjin city.
• Address:
  • Yongle Bridge, Sanchahekou, Hongqiao District, Tianjin
• Transportation:
  • Take Metro Line 1 to the Northwest Corner Station, then transfer to Bus Route 516 City Line and get off at Yongle Bridge Station, then walk to the destination; from the exhibition hall, you can reach the destination by transferring between the metro and the bus. If taking a taxi, the driver will be familiar with the route, making it convenient and quick, with a fare of approximately 20-30 yuan.

6.3 Shopping Destinations

6.3.1 Heping Road Commercial Street

• Features:
  • One of Tianjin’s most bustling commercial streets, it features a variety of brand-name stores, shopping malls, and specialty shops to cater to diverse shopping needs.
• Shopping Recommendations:
  • Purchase fashionable clothing, Tianjin-themed souvenirs, traditional handicrafts, and more.
• Address:
  • Heping Road, Heping District, Tianjin (north of Tianjin Station to Yingkou Road)​
• Transportation:
  • There are buses near the exhibition hall that go directly to Heping Road Commercial Street. Take bus routes 901 or 611 and get off at Heping Road Station; or take Metro Line 3 and get off at Heping Road Station, which is right next to the commercial street.

6.3.2 Florence Town

• Features:
  • A luxury outlet mall inspired by classic Italian architectural style, offering not only shopping discounts but also a rich Italian ambiance.
• Shopping Recommendations:
  • Numerous international brand discount stores, including clothing, footwear, and luggage.
• Address:
  • North side of Qianjin Road, Wuqing District, Tianjin (intersection of Cuiheng Road and Qianjin Road)
• Transportation:
  • From the exhibition hall, you can take a dedicated bus shuttle to Florence Town, such as the Florence Town Free Shuttle (please check departure times and locations in advance); alternatively, you can take the Beijing-Tianjin Intercity Train from Tianjin Station to Wuqing Station, then walk or take a short shuttle bus to the town, with a journey time of approximately 20 minutes.

6.4 Other Accommodation Recommendations

6.4.1 Hotels Along the Haihe River

• Features:
  • Prime location with views of the Haihe River, convenient transportation, and proximity to multiple attractions and food streets.
• Recommended Hotels:
  • Tianjin Lishunde Grand Hotel (Address: No. 33 Tai’erzhuang Road, Heping District, Tianjin) and Tianjin Haihe Holiday Hotel (Address: No. 38 Jubbu Road, Hebei District, Tianjin), among others, are popular choices among international guests.
• Booking Methods:
  • Bookings can be made through major online travel platforms or the hotels’ official websites.

6.4.2 Guesthouses near the Five Avenues

• Features:
  • Beautiful environment, exotic atmosphere, and the opportunity to experience local life.
• Recommended guesthouses:
  • Tianjin Five Avenues Style Guesthouse (Address: Near 166 Machang Road, Heping District, Tianjin) and Tianjin Munan Road Boutique Guesthouse (Address: 78 Munan Road, Heping District, Tianjin), etc.
• Booking Methods:
  • Search for homestays near the Five Avenues on homestay booking platforms, and select suitable accommodations based on reviews and photos for booking.

We hope this guide helps you enjoy a pleasant stay in Tianjin and fully experience the charm and vibrancy of this city!